Terry Cole, the landlord of the Royal Oak, close to the Bank’s brewery in Wolverhampton, said his pub sold about 200 pints of Bank’s Mild every week.
But Mr Cole said he believed there was “no going back” and that “the world has to evolve and we have to move on”.
He said he could understand why the company was cutting its less popular ales and he understood Bank’s Mild was a “regional ale”, popular in the West Midlands, but not as popular nationally.
Nevertheless, he said his customers would be disappointed and it would be hard to find a replacement.
Warinder Juss, the Labour MP for Wolverhampton West, said he was “concerned” by the decision to cut back on some beers.
He said: “I’ve had a meeting with them where they assured me that they will continue to brew the Bank’s beer that we are all accustomed to.”
“I think it is probably time to have another meeting with them,” he added.